Evaluation of Military Fuel Potential to Produce Male Reproductive Toxicity. G. B. Briggs and W. A. Price, GEO-Centers Inc.; and A. F. Walsh, W. K. Alexander, and K. R. Still, NHRC/TD
The navy is converting to JP-8 jet fuel for universal use in planes and certain vehicles. Studies to evaluate the toxicology of military fuel vapors have been reported and permissible exposure levels developed. The potential for JP-8 and JP-5 to produce changes in sperm quality parameters was evaluated in rats following exposure by inhalation for six weeks. The Computer-Assisted Sperm Analysis (CASA) system was used to detect sperm quality end points. Results from this study indicate that inhalation exposure to JP-8 and JP-5 jet fuel had no significant influence on sperm maturation, total counts, viability, motility or morphology in rats following six weeks of exposure at 1000 mg/cubic meter of air. These data will be included in the continuing program to characterize the toxicity of military fuels and formulate permissible exposure levels.
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