Decision Making Support System for Health Risk Management. K. L. Atoyev, Glushkov Institute of Cybernetics of NAS of Ukraine
The medical computer system (MCS) for health risk estimation and management is elaborated. It includes some mathematical models that describe impact of negative environmental factors (NEF) on health deterioration (HD). The risk assessment of HD is developed on the base of theory of catastrophes and optimum control. Created computer technology allows on the isolated data of clinical inspections to receive quantitative accounts of HD risk ranking. The critical values of integrated parameters describing immune, endocrine, energetic and other systems are calculated. At approximation to ones the HD risk sharply grows. Created computer technology also allows: 1) to estimate efficiency of carried out therapy; 2) to carry out the comparative analysis to reveal most of "#34 link in reserve opportunities of organism; 3) to predict consequences of various therapeutical schemes of patient’s treatment. The computer system was used to investigate the role of metabolic and hormonal mechanisms of neuro-immune-endocrine control (NIEC) in organism reactions on stress. The following tasks were examined: 1) the comparative analysis of dynamics of NIEC at some kinds of thyroid system pathology; 2) research of influence of irradiation doze on mechanisms of formation of violations of thyroid gland function; 3) the ranking of various links of thyroid system on sensitivity to radiation impacts. The ranking of sensitivity of different links of NIEC to radiation action has allowed determining a sequence of response of various control links on an increased level of radiation. The obtained results allow determining the most probability consequence of changes that lead to HD.
Work supported by The Ukrainian Ministry of Emergencies under contract 17/13aH-99.04.
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