Approaches for Compiling and Disseminating Exposure Assessment Information. P. J. Hakkinen and A. Wullenweber, Toxicology Excellence for Risk Assessment (TERA), OH
Resources to support evaluations of human exposures to chemicals are diverse and constantly evolving. In addition, the settings in which such data are needed to provide useful context for regulatory and other decision-making are expanding. Initiatives in the United States that have spurred the need for methods for conducting comprehensive exposure assessments include the Food Quality Protection Act (which requires complex evaluations of aggregate or cumulative exposures in a variety of settings), the Toxics Release Inventory and associated efforts to evaluate the potential exposure posed by the listed emissions, the toxicity data that will be generated by the High Production Volume chemical testing program and associated efforts to provide some exposure-related context, the National Exposure Report Card summarizing biomonitoring data collected by the Centers for Disease Control and Prevention, and environmental justice evaluations. Although data for some types of exposure assessments have bee n extensively compiled and disseminated (e.g., exposure information supporting evaluations of environmental releases such as Superfund sites), other data are more widely dispersed and syntheses of the data are either not available or are difficult to obtain (e.g., data regarding use of various consumer products). Approaches for compiling and disseminating exposure assessment information will be reviewed, including the Web-accessible information recently developed by the Alliance for Chemical Awareness.
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