Associations Between Air Pollution and Health in Children with Asthma. J. Q. Koenig, J. Kaufman, J. H. Sullivan, C. A. Trenga, and K. Jansen, University of Washington
A panel of 19 children with asthma was followed from December 2000 through May 2001. The subjects had mild to moderate asthma and were 7 –12 years of age. The exposure assessment aspects of the study are presented elsewhere. The measures of health status taken during 10 day sessions were lung function, symptoms, medication use, and exhaled nitric oxide concentration. A computerized spirometer was used so that a wide range of pulmonary functions could be measured. Lung function was measured in the morning and the evening by the child and in the afternoon by a visiting technician. This included FEV1, FVC, PEF and flow-volume curves. Approximately half of the subjects repeated the 10-day session in a second season and several completed three separate sessions. Health outcomes were tested for associations with several measures of particulate air pollution and co-pollutants at personal, indoor, outdoor of residence and central sites. Size fractions measured were PM10, PM2.5, PM1.0 (using a light scattering instrument) and both elemental and organic carbon. Particulate matter concentrations were elevated during the winter heating season due to use of residential wood burning.
This research was funded by EPA NW Research PM Center grant # 827355 and EPA cooperative agreement # 827177.
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