Assessing Exposures to Pesticide Inert Ingredients. T. H. Brennan, K. H. Boyle, and K. B. Leifer, US Environmental Protection Agency, DC
The U.S. Environmental Protection Agency; Office of Pesticide Programs (OPP); Health Effects Division, and the Registration Division, have developed a strategy for assessing exposures to pesticide inert ingredients in products that are used at residential settings. OPP believes the best way to assess exposure to pesticide inert ingredients is to use a "hybrid" of exposure assessment techniques, including those methods used to assess pesticide active ingredients, consumer products, and industrial chemicals. Thus, OPP has developed a strategy for inert ingredients that integrates risk assessment information and models developed to support three major Agency regulations: (1) the Food Quality Protection Act, (2) the Federal Insecticide, Fungicide, and Rodenticide Act, and (3) the Toxic Control Substances Act. In addition to identifying relevant exposure analysis techniques from across the Agency, OPP has a new inert ingredients database specifically tailored for this project. The database will be used to determine: (1) what are the inert ingredients functional use categories in a given pesticide products; and, (2) what is the weight fraction of each of the inert ingredients functional use categories for various pesticide product formulations. This presentation will focus on the "hybrid" exposure assessment approach used for assessing pesticide inert ingredients, as well as an summary of the OPP inert ingredients data base development activities.
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